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Symbol
Name
ID
E2f4
E2F transcription factor 4
MGI:103012
Phenotype annotations related to digestive/alimentary system
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Neoplasm of the rectum
Colon cancer
Intestinal polyposis
Neoplasm of the stomach
Constipation
Nausea and vomiting
Neoplasm of the liver
Hepatocellular carcinoma
Disease(s) Associated with E2F4
Lynch syndrome

Mouse Phenotypes
abnormal colon goblet cell morphology
abnormal small intestine goblet cell morphology
abnormal intestine morphology
abnormal intestinal epithelium morphology
abnormal intestinal mucosa morphology
abnormal crypts of Lieberkuhn morphology
abnormal small intestine morphology
abnormal small intestinal villus morphology
decreased small intestinal villus size
Availability Mouse Genotype
E2f4tm1Jrn/E2f4tm1Jrn
E2f4tm1Lees/E2f4tm1Lees

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory